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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T73957 | PROTAC Bcl-xL degrader-1 | ||
PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits to... | |||
T39910 | Desmorpholinyl Navitoclax-NH-Me | Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me | BCL |
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2]. | |||
T18363 | Monoethyl pimelate | Others , PROTAC Linker | |
Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1]. | |||
T73826 | PZ703b hydrochloride | ||
PZ703b hydrochloride, a Bcl-xl PROTAC degrader, effectively induces apoptosis and curbs the proliferation of cancer cells. It is primarily utilized in the study of bladder cancer [1] [2]. |